Medicine Graduate Courses

M215. Interdepartmental Course: Tropical Medicine. (2) (Same as Pathology M215 and Pediatrics M215.) Lecture, two and one half hours. Preparation: basic courses in microbiology and parasitology of infectious diseases in School of Medicine or Public Health. Study of current knowledge about diseases prevalent in tropical areas of the world. Major emphasis on infectious diseases, with coverage of problems in nutrition and exotic noninfectious diseases. Syllabus supplements topics covered in classroom. S/U grading.

M256. Interdisciplinary Response to Infectious Disease Emergencies: Medicine Perspective. (4) (Same as Community Health Sciences M256, Nursing M298, and Oral Biology M256.) Lecture, three hours; discussion, one hour. Designed to instill in professional students ideas of common emergency health problems and coordinated response, with specific attention to bioterrorism. Examination of tools to help students prevent, detect, and intervene in infectious disease emergencies. Interdisciplinary sessions also attended by students in Schools of Dentistry, Nursing, and Public Health during weeks two through five. Letter grading.

M260A-M260B. Methodology in Clinical Research I, II. (4-4) (Same as Biomathematics M260A-M260B.) Lecture, four hours. Recommended preparation: MD, PhD, or dental degree. Requisites: Biomathematics 170A, 265A. Course M260A is requisite to M260B. Presentation of principles and practices of major disciplines underlying clinical research methodology, such as biostatistics, epidemiology, pharmacokinetics. S/U or letter grading.

M260C. Methodology in Clinical Research III. (4) (Same as Biomathematics M260C.) Discussion, four hours. Recommended preparation: MD, PhD, or dental degree. Presentation of principles and practices of major disciplines underlying clinical research methodology, such as biostatistics, epidemiology, pharmacokinetics. S/U or letter grading.

M261. Responsible Conduct of Research Involving Humans. (2) (Same as Biomathematics M261.) Lecture, two hours; discussion, two hours. Preparation: completion of one basic course in protection of human research subjects through Collaborative Institutional Training Initiative. Discussion of current issues in responsible conduct of clinical research, including reporting of research, basis for authorship, issues in genetic research, principles and practice of research on humans, conflicts of interest, Institutional Review Board (IRB), and related topics. S/U or letter grading.

M263. Clinical Pharmacology. (2) (Same as Biomathematics M263 and Psychiatry M263.) Lecture, two hours. Preparation: completion of professional health sciences degree (MD, DDS, DNSc, or PhD). Overview of principles of clinical pharmacology, especially as they relate to clinical and translational medicine and to advances in contemporary medicine such as targeting, gene therapy, and genomics. Letter grading.

M270C. Advanced Modeling Methodology for Dynamic Biomedical Systems. (4) (Same as Bioengineering M296A and Computer Science M296A.) Lecture, four hours; outside study, eight hours. Requisite: Electrical Engineering 141 or 142 or Mathematics 115A or Mechanical and Aerospace Engineering 171A. Development of dynamic systems modeling methodology for physiological, biomedical, pharmacological, chemical, and related systems. Control system, multicompartmental, noncompartmental, and input/output models, linear and nonlinear. Emphasis on model applications, limitations, and relevance in biomedical sciences and other limited data environments. Problem solving in PC laboratory. Letter grading.

M270D. Optimal Parameter Estimation and Experiment Design for Biomedical Systems. (4) (Same as Bioengineering M296B, Biomathematics M270, and Computer Science M296B.) Lecture, four hours; outside study, eight hours. Requisite: course M270C or Bioengineering CM286 or Biomathematics 220. Estimation methodology and model parameter estimation algorithms for fitting dynamic system models to biomedical data. Model discrimination methods. Theory and algorithms for designing optimal experiments for developing and quantifying models, with special focus on optimal sampling schedule design for kinetic models. Exploration of PC software for model building and optimal experiment design via applications in physiology and pharmacology. Letter grading.

M270E. Advanced Topics and Research in Biomedical Systems Modeling and Computing. (4) (Same as Bioengineering M296C and Computer Science M296C.) Lecture, four hours; outside study, eight hours. Requisite: course M270D. Research techniques and experience on special topics involving models, modeling methods, and model/computing in biological and medical sciences. Review and critique of literature. Research problem searching and formulation. Approaches to solutions. Individual MS- and PhD-level project training. Letter grading.

M290A-M290B. Child Abuse and Neglect. (2-2) (Same as Community Health Sciences M245A-M245B-M245C, Dentistry M300A-M300B-M300C, Education M217G-M217H-M217I, Law M281A-M281B, Nursing M290A-M290B-M290C, and Social Welfare M203F-M203G-M203H.) Lecture, two hours. Course M290A is requisite to M290B. Intensive interdisciplinary study of child physical and sexual abuse and neglect, with lectures by faculty members of Schools of Dentistry, Law, Medicine, Nursing, and Public Health and Departments of Education and Psychology, as well as by relevant public agencies. Letter grading.