- Julio J. Frenk Mora, Chancellor (effective January 1, 2025)
- Darnell M. Hunt, Executive Vice Chancellor and Provost; Chancellor (Interim)
- Stephen J. Agostini, Vice Chancellor; Chief Financial Officer
- Michael J. Beck, Administrative Vice Chancellor
- Monroe Gorden, Jr., Vice Chancellor, Student Affairs
- Michael S. Levine, Vice Chancellor, Academic Personnel
- John C. Mazziotta, Vice Chancellor, Health Sciences
- Ina M. Bryant, Vice Chancellor, Legal Affairs (Interim)
- Mary Osako, Vice Chancellor, Strategic Communications
- Rhea Turteltaub, Vice Chancellor, External Affairs
- Roger M. Wakimoto, Vice Chancellor, Research
- Mitchell J. Chang, Vice Provost, Equity, Diversity, and Inclusion (Interim)
- C. Cindy Fan, Vice Provost, International Studies and Global Engagement
- Erin Sanders O'Leary, Vice Provost, Teaching and Learning
- David K. Yoo, Vice Provost, Institute of American Cultures
- Athena N. Jackson, University Librarian
- Kate Jakway-Kelly, University Registrar (Interim)