<p>(Same as Chemistry CM259.) Lecture, four hours. Requisite: Chemistry 153B. RNA polymerase structures and mechanisms; promoter recognition and transcription cycle; mechanisms of activation; transcriptional poising and elongation control; Mediator of transcription; chromatin remodeling and modification; epigenetic regulation; cotranscriptional and transcription-coupled RNA processing; impact of transcription on mRNA processing and stability; nuclear export of mRNA. S/U or letter grading.</p>

Biological Chemistry

The school is a groundbreaking community of problem solvers, caregivers, innovators, and life-long learners with a noble mission: to heal humankind by delivering leading-edge research, education, patient care, and community engagement.

David Geffen School of Medicine

The department studies cellular, molecular, and developmental biology; molecular genetics and genetic engineering; aspects of the health sciences; and classic topics of metabolism, enzymology, and biomolecular structure.

General Catalog

Mechanisms of Gene Regulation

BIOLCHM259

4 units