<p>Lecture, three hours. Enforced requisite: course 14D or 30B with a grade of C– or better. Overview of drug discovery process with focus on transition metal catalysis in synthesis of medicines. Discussion of process by which drugs are discovered, from lead optimization to process development. Introduction to transition metal catalysis, area of critical importance in modern drug development. Study of fundamental concepts of transition metal catalysis and how catalysis has played transformative role in synthesis of modern medicines. Particular attention throughout to discussion of case studies that emphasize broad impact of medicinal chemistry and importance of catalysis in drug discovery. Highlights how organic chemistry can impact world around us, particularly in development of pharmaceuticals. P/NP or letter grading.</p>

Chemistry and Biochemistry

Combining rigorous, inclusive pedagogy with opportunities for co-curricular activities—including research, internships, and community engagement—the College provides students with diverse learning experiences that helps them thrive, become critical thinkers, and transform society.

College of Letters and Science

Chemistry is concerned with the composition, structure, and properties of substances, the transformations of these substances into others by reactions, and the kinds of energy changes that accompany these reactions.

General Catalog

Catalysis in Modern Drug Discovery

CHEM101

4 units