<p>(Same as Bioengineering CM186, Computer Science CM186, and Ecology and Evolutionary Biology M178.) Lecture, four hours; laboratory, two hours; discussion, one hour. Requisites: Life Sciences 30A, 30B, Mathematics 32A or M32T, 33A, and 33B; or Mathematics 31A, 31B, 32A or M32T, 33A, and 33B. Dynamic biosystem modeling and computer simulation methods for studying biological/biomedical processes and systems at multiple levels of organization. Intermediate linear and nonlinear control system, multicompartmental, epidemiological, pharmacokinetic, and other biomodeling methods applied to life sciences problems at molecular, cellular, organ, and population levels. Both theory- and data-driven modeling, with focus on translating biomodeling goals and data into dynamical mathematical models, and implementing them for simulation, quantification, and analysis. Numerical simulation, optimization, and parameter identifiability and search algorithms, with model discrimination and analysis and software exercises in PC laboratory assignments. Letter grading.</p>

Computational and Systems Biology

Combining rigorous, inclusive pedagogy with opportunities for co-curricular activities—including research, internships, and community engagement—the College provides students with diverse learning experiences that helps them thrive, become critical thinkers, and transform society.

College of Letters and Science

The interdisciplinary major trains students to solve basic and applied biological problems by combining the sciences, mathematics, and computing.

General Catalog

Computational Systems Biology: Modeling and Simulation of Biological Systems

C&S BIO M186

5 units