<p>Lecture, two hours. Limited to Genetic Counseling students, and open to medical genetics, molecular and cytogenetics fellows with permission. Introduction to next generation sequencing (NGS) technologies, bioinformatics pipeline for analyzing NGS data, clinical interpretation of variants using ACMG guidelines, various databases used for variant interpretation, interpretation of exome clinical report, process of communicating results to patients and ethical, legal, and social implications (ELSI) of personal genomics. Offers hands-on laboratory-style experience to interpreting human exome/genome variants for genetics professionals and trainees. Students acquire necessary background to understand technical and analytical aspects of exome/genome test, make informed decisions about clinically relevant variants, and communicate results to patient or patient’s family. Attendance at weekly Genome Data Board meeting is required. Letter grading.</p>

Human Genetics

The school is a groundbreaking community of problem solvers, caregivers, innovators, and life-long learners with a noble mission: to heal humankind by delivering leading-edge research, education, patient care, and community engagement.

David Geffen School of Medicine

The graduate program trains the next generation of leaders in human genetics.

General Catalog

Translational Genomics

HUM GEN 410

3 units