<p>Lecture, three hours; discussion, one hour. Requisite: course 111B. Discussion of cellular and molecular players involved in cardiac morphogenesis, postnatal heart growth, and cardiac regeneration, to better understand emergence of cardiac diseases such as congenital heart disease, coronary artery disease, and atherosclerosis. Use of primary literature to highlight modern genetic tools such as transgenic animal models and sequencing technologies to investigate how various cardiac cell lineages and/or gene perturbations contribute to cardiac pathophysiology such as cardiomyocyte death, cardiac fibrosis, and vascular dysfunction. Letter grading.</p>

Physiological Science

Combining rigorous, inclusive pedagogy with opportunities for co-curricular activities—including research, internships, and community engagement—the College provides students with diverse learning experiences that helps them thrive, become critical thinkers, and transform society.

College of Letters and Science

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The cornerstone of the physiological science curriculum is vertebrate physiology, with emphases on integrative functions.

General Catalog

Cellular and Molecular Insights into Cardiovascular Development and Disease

PHYSCI 109

4 units